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Deep Brain Stimulation and Depression Do not Tempt
A LIGHTNING OF HOPE FOR DEPRESSION
This entry is research being done on the application of electricity to the treatment of depression, a more effective than the current electroshock
LA RESEARCH. EXPECTATIONS.
deep brain stimulation (DBS) is a novel technique for treating many diseases, including severe depression
.
The technique, which is already effectively in Parkinson's disease is still experimental in the case of depression, while "prospects are particularly promising" and "remarkable success", increasing the evidence for, as Kringelbach and Aziz.
The indication, according to Dr. Volker Sturm, is for severe depression, long duration and who have not responded to other treatments.
The indication, according to Dr. Volker Sturm, is for severe depression, long duration and who have not responded to other treatments.
Many research teams are multiplying around the world working on the ECP. In Spain, the Sant Pau hospital recently completed the intervention in 8 patients with major depression, with successful results.
During the experiment have been really dramatic changes in depressed patients. "A depressed woman felt his world literally glowed as the electrode was activated, "the doctors tell Kringelbach and Aziz. Another woman with a paralyzing anxiety that prevented him from leaving home and lead a normal life, is now, as is healed. Patients, mostly, recover vital energy renewed.
FUNDAMENTALS OF ECP
In the brain there are a multitude of neural circuits, assemblies of neurons linked by electrical impulses and neurotransmitters. Some of these neural circuits are directly related to the mood of the individual. In the depressed patient, these circuits are over-excited, ie, the electrical activity is greater than what would be normal and desirable. ART
During the experiment have been really dramatic changes in depressed patients. "A depressed woman felt his world literally glowed as the electrode was activated, "the doctors tell Kringelbach and Aziz. Another woman with a paralyzing anxiety that prevented him from leaving home and lead a normal life, is now, as is healed. Patients, mostly, recover vital energy renewed.
FUNDAMENTALS OF ECP
In the brain there are a multitude of neural circuits, assemblies of neurons linked by electrical impulses and neurotransmitters. Some of these neural circuits are directly related to the mood of the individual. In the depressed patient, these circuits are over-excited, ie, the electrical activity is greater than what would be normal and desirable. ART
DBS involves the implantation in the brain electrodes which are connected to a small battery located in the upper chest (like a pacemaker, but for the brain).
Surgery was performed piercing a small hole in the skull and inserting electrodes for him, now located in the brain with pinpoint accuracy to be (it is critical that the electrodes affect the neurons that are affected and not others that have nothing to do with depression.)
Although not yet known what the most effective point to insert in the case of depression, the nucleus accumbens (one of the main centers of the central system of reward) seems one of the likeliest candidates.
Surgery was performed piercing a small hole in the skull and inserting electrodes for him, now located in the brain with pinpoint accuracy to be (it is critical that the electrodes affect the neurons that are affected and not others that have nothing to do with depression.)
Although not yet known what the most effective point to insert in the case of depression, the nucleus accumbens (one of the main centers of the central system of reward) seems one of the likeliest candidates.
The battery sends electrical current to the electrode which causes the excitation of the target area of \u200b\u200bthe brain disappears, returning to a normal electrical activity. Thus, the symptoms of depression (anxiety, emptiness, inability to enjoy or anhedonia, apathy, etc.) Disappear.
The patient should bring the battery and electrodes, the thorax and brain, respectively, so indefinitely. The same patient can vary the amount of current through a device that purpose, being able to completely stop the artificial electrical stimulation (in this case, the symptoms return immediately). SIDE EFFECTS
treatment only affects neurons under the influence of the electrodes, unlike drugs, which flooded the entire brain, which have unwanted side effects. Another advantage of reversibility, if something goes wrong, it limits or eliminates the electrical impulse.
treatment only affects neurons under the influence of the electrodes, unlike drugs, which flooded the entire brain, which have unwanted side effects. Another advantage of reversibility, if something goes wrong, it limits or eliminates the electrical impulse.
In patients who experienced brain bleeding occurred (between 1% and 3% of cases) especially in cases of older people. Such bleeding can cause a stroke, with paralysis of members included.
Other side effects are infections that have been always curable.
NOTE 1: Morten L. Kringelbach is a researcher at the University of Oxford. Tipu Z. Aziz. is a research pioneer of deep brain stimulation Volker Sturm is Professor at the Neurosurgical University Clinic in Heidelberg.
NOTE 2:
Information taken mainly from:
This video networks RTVE program
Magazine "Mind and Brain", number 42/2010
Other side effects are infections that have been always curable.
NOTE 1: Morten L. Kringelbach is a researcher at the University of Oxford. Tipu Z. Aziz. is a research pioneer of deep brain stimulation Volker Sturm is Professor at the Neurosurgical University Clinic in Heidelberg.
NOTE 2:
Information taken mainly from:
This video networks RTVE program
Magazine "Mind and Brain", number 42/2010
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